There is still much uncertainty about the pathophysiology of hypertension. A small number of patients (between 2% and 5%) have an underlying renal or adrenal disease as the cause for their raised blood pressure. In the remainder, however, no clear single identifiable cause is found and their condition is labelled “essential hypertension”.
In response to this pressure overload inside the heart, heart muscle cells may respond by getting thicker along the inner walls of the heart. This thickened wall can cause the left chamber to weaken, stiffen and lose elasticity, which may prevent healthy blood flow.
Left ventricular hypertrophy is more common in people who have uncontrolled high blood pressure. But no matter what your blood pressure is, developing left ventricular hypertrophy puts you at higher risk of a heart attack and stroke. Treating high blood pressure can help ease your symptoms and may reverse left ventricular hypertrophy.