Once H. pylori colonizes the stomach, it replicates and releases toxins which can cause diseases such as gastritis, peptic ulcer, or gastric malignancies. Helicobacter Pylori is a Gram-negative, microaerophilic bacterium found in the stomach. 3D illustration. 3D rendering. Image Credit: Tatiana Shepeleva / Shutterstock
Morphology Helicobacter pylori is a helix -shaped (classified as a curved rod, not spirochaete) Gram-negative bacterium about 3 μm long with a diameter of about 0.5 μm.
Rather, it is the interaction between the different pro- and anti-inflammatory polymorphisms, the immune status of the host, and the characteristics of the colonizing H. pylori strain that jointly determine disease outcome. The role of H. pylori in gastroduodenal disease has become firmly established.