The US Diabetes Prevention Program included women with a history of GDM as one risk factor for diabetes mellitus.
With obesity becoming a global epidemic, the assessment of the strength of the evidence supporting the impact of overweight and obesity in GDM could allow the identification of women at high risk for adverse outcomes and allow better prevention.
A hyperglycemic environment is associated with oxidative stress, and GDM women have been reported to overproduce free radicals and have impaired free-radical scavenging mechanisms [139]. ROS inhibit insulin-stimulated glucose uptake by interfering with both IRS-1 and GLUT4 [140].
Gdm Risk Factors Image Diagram - Chart - diagrams and charts with labels. This diagram depicts Gdm Risk Factors Image